Xylocaine 10mg Pump Spray 10% Lidocaine is a Pharmacy Only Medicine. One spray dose of XYLOCAINE PUMP SPRAY contains lignocaine base 10 mg and is indicated for the prevention of pain associated with injections, impressions, suturing intra-oral lacerations, X-Rays and removal of calculus.
CONTRAINDICATIONS: Known hypersensitivity to local anaesthetics of the amide type or to any of the excipients.
SPECIAL WARNINGS AND PRECAUTIONS FOR USE Excessive dosage, or short intervals between doses, may result in high plasma levels and serious adverse effects. Absorption from mucous membranes is variable but is especially high from the bronchial tree. Such applications may therefore result in rapidly rising or excessive plasma concentrations, with an increased risk for toxic symptoms, such as convulsions.
INTERACTIONS WITH OTHER MEDICINES AND OTHER FORMS OF INTERACTION: Lignocaine should be used with caution in patients receiving other local anaesthetics or agents structurally related to amide-type local anaesthetics, e.g. anti-arrhythmics such as mexiletine and tocainide, since the toxic effects are additive. Specific interaction studies with lignocaine and anti-arrhythmic medicines class III (e.g. amiodarone) have not been performed, but caution is advised. Medicines that reduce the clearance of lignocaine (e.g. cimetidine or betablockers) may cause potentially toxic plasma concentrations when lignocaine is given in repeated high doses over a long period of time. Such interactions should therefore be of no clinical importance following short term treatment with lignocaine (e.g. XYLOCAINE PUMP SPRAY) at recommended doses.
Fertility, pregnancy and lactation: It is reasonable to assume that a large number of pregnant women and women of child-bearing age have been given lignocaine. No specific disturbances to the reproductive process have so far been reported, e.g. no increased incidence of malformations. Like other local anaesthetics, lignocaine may enter the mother's milk, but in such small amounts that there is generally no risk of this affecting the neonate.
Effects on ability to drive and use machines: Depending on the dose, local anaesthetics may have a very mild effect on mentalfunction and may temporarily impair locomotion and co-ordination.
Dose: Refer to datasheet for application specific dosing.
For full information on dosage, contraindications, precautions, interactions and adverse effects please refer to the data sheet available at www.medsafe.govt.nz or by clicking on the link provided with this product. NZ Sponsor: Pharmacy Retailing (NZ) Limited Trading as Healthcare Logistics. Auckland
NP21454 - Aug 2024